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2017 Science of Ingredients: Sabinsa Corporation

Once Again Nut ButterNOW Private Label

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Digestive Enzymes Benefit Much More Than Digestion

Healthy digestion—you notice, or perhaps experience it only when you don’t have it! Given the fact that today we are experiencing drastic changes in our lifestyle and diet habits, maintaining a healthy digestive system is vital. Digestive enzymes are currently gaining popularity in the digestive health supplements category, which are known to make a significant difference for your digestive health beyond just providing basic nutrition.

Enzymes are the essential part of any chemical reactions that take place in the body. Various biological reactions, such as digesting food, activities of the brain, cellular energy and repair process of tissues, organs and cells are regulated by different types of enzymes.

Since ancient days, people are well aware of various health and nutritional benefits of enzymes, which is evident from the fact that different civilizations have been using enzymes in one form or the other as a part of their everyday practices. Today, people are convinced about enzymes’ role in improving overall health and wellness in general and gut/digestive health in particular—thanks to clinical-based evidences. As a result, demand for enzyme-based products is on the rise in the nutritional supplement industry, as per recent sales statistics. Further research would attract more and more individuals to embrace the enormous health benefits that enzymes offer.

It is believed that in some people, the body’s natural ability to produce enzymes starts declining very early (as early as age 25). Hence, supplementing with digestive enzymes would not only take care of your digestive health but also would support in weight management, joint health, management of circulatory problems, relieving muscle soreness and many more.

Digestive enzyme supplements help balance the digestive process, particularly in people who experience chronic gastrointestinal discomfort, support healthy immune functions and help in the breakdown of fats, proteins and carbohydrates.1

The modern day lifestyle is taking its toll by causing number of discomforts to our body. For example, disturbed activity of digestive enzymes, enzyme insufficiency, etc. Hence, maintaining adequate levels and optimal activity of digestive enzymes should be the top priority in everybody’s list—to address several health-related issues.

DigeZyme: Full-spectrum Multi-Enzyme Complex

Sabinsa has come up with a proprietary combination of enzymes called DigeZyme, a multi-enzyme complex, clinically proven to be helpful in supporting a healthy digestive system: cellulase for fibrous food, lactase for individuals with lactose intolerance, and αα-amylase, lipase and protease for those who have difficulty in digesting carbohydrates, fats and proteins, respectively.

Science-backed Efficacy

a) For Digestive Health: A recent clinical study involving patients diagnosed with functional dyspepsia (FD), a chronic disorder of sensation and movement (peristalsis) in the upper digestive tract, demonstrated that DigeZyme was efficacious and significantly alleviated symptoms related to FD in comparison to placebo group with no reports on adverse events.

b) For DOMS (Delayed Onset Muscle Soreness): In a recently published double-blind, placebo-controlled clinical trial it was observed that DigeZyme was able to decrease the associated pain and tenderness induced by exercise. Decrements were also observed in McGill Pain Questionnaire showing high significance in the active arm (Figures 1 and 2). There was also a declining trend in the level of pro-inflammatory biomarkers (creatine kinase and lactate dehydrogenase).2

Suggested Use Level

DigeZyme was found to be safe and effective for the mentioned applications, at a recommended daily dosage of 150 mg per day.

DigeZyme is Formulation-friendly

• Vegan: Derived from non-animal sources
• Each enzyme in the blend is food-grade, non-GMO (genetically modified organism) and gluten free
• Adheres to the most stringent international standards and regulatory norms
• Resistant to the action of gastric juices, while retaining optimal activity
• Safe, traceable origins, validated quality and science-backed efficacy


1. Roxas M. Alternative Medicine Review. 2008; 13(4):307-14.

2. Majeed M et al. Sports Nutr Ther. 2016; 1:113. doi: 10.4172/2473-6449.1000113.

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