Phone: (914) 701-4500
Email: [email protected]
Website: www.nutrition21.com

Years of Nutrition, Biotechnology and Pharmaceutical Experience

Nutrition 21, a wholly owned subsidiary of JDS Therapeutics, has a longstanding reputation as a leader in the nutritional supplement industry. Nutrition 21 is a developer and marketer of efficacious, high-value, and clinically substantiated ingredients for dietary supplements, medical foods, and nutritional bars and beverages. Its flagship branded ingredient is Chromax chromium picolinate and its newest sports nutrition ingredient is Nitrosigine bonded arginine silicate. In 2013, Nitrosigine received FDA (U.S. Food and Drug Administration) New Dietary Ingredient (NDI) Notification status and is now affirmed as generally recognized as safe (GRAS) for use in nutritional bars and beverages.

With many years of nutrition, biotechnology and pharmaceutical experience, Nutrition 21’s scientific platform has created unique, patented products that are safe and clinically effective. Rigorous preclinical and clinical trials are a key part of its product development strategy to ensure product safety and consumer trust. Nutrition 21 ingredients are compliant with USP (United States Pharmacopeia) and E.U. quality and safety standards.

Nutrition 21 currently holds more than 100 domestic and international issued and pending patents for its products. Many support unique claims associated with, among others, glucose metabolism, weight management, brain health, cardiovascular health and sports nutrition.

Nitrosigine Bonded Arginine Silicate

Nitrosigine is a patented complex of bonded arginine silicate with FDA NDI notification status and is affirmed as GRAS. Nitrosigine is clinically tested and safe for use in products that benefit fitness focused consumers and athletes engaged in muscle-building training programs. This non-stimulant ingredient is made in the U.S. and has been shown to significantly boost nitric oxide levels. Increased nitric oxide levels are a key factor in generating greater blood flow to working muscles, supporting overall cardiovascular and muscular health. Nitrosigine is fast acting, producing increased arginine levels in as quickly as 30 minutes, and long lasting, delivering benefits for up to three hours—with just a single dose.

Nitrosigine is supported by category-specific, preclinical and clinical studies. Abstracts from clinical studies were presented at the renowned Experimental Biology annual meetings in 2014 and 2015. Clinical study findings support the use of Nitrosigine as a bioavailable source of arginine and silicon and demonstrate connections between Nitrosigine supplementation and various blood protein markers that contribute to the understanding of the ingredient’s mechanism of action. Findings from additional Nitrosigine clinical studies are scheduled for release in 2015.

Nutrition 21 offers co-promotional opportunities for our key customers, helping drive sales for products formulated with Nitrosigine. An integrated program with major consumer publications generates millions of consumer impressions per month, both in print and online. This targeted awareness campaign drives traffic to the company’s dedicated consumer website www.nitrosigine.com and communicates the powerful benefits of Nitrosigine directly with fitness-focused consumers.

Chromax Chromium Picolinate

Not all chromium is the same. Nutrition 21’s Chromax chromium picolinate is supported with more than 50 human clinical studies including 2,300-plus human subjects, affirmed for GRAS doses up to 2000 mcg per day, and has 35 non-rejected DSHEA (Dietary Supplement Health and Education Act of 1994) claims. With more than 20 active and pending composition and use patents, Chromax chromium picolinate, made in the U.S., is a clinically efficacious form of dietary chromium that has been reviewed extensively for safety and efficacy. Several clinical studies have shown that Chromax chromium picolinate is significantly better absorbed than other forms of dietary chromium. In 2015, Chromax chromium picolinate was used by the USP to create and validate a new assay for testing chromium levels.

There is a vast body of evidence supporting the role of Chromax chromium picolinate in healthy glucose metabolism and in maintaining healthy blood glucose levels. Additionally, a number of studies have contributed to the understanding of Chromax chromium picolinate’s role in brain health and have uncovered key insights into the beneficial role Chromax chromium picolinate supplementation may play in the metabolic and biochemical pathways of the brain.

The body of scientific evidence behind Chromax chromium picolinate provides Nutrition 21’s customers with marketable substantiated claims and numerous health benefits for the consumer. Chromax chromium picolinate is a perfect nutrient to formulate into products positioned to address health and lifestyle issues that are of increasing concern to consumers, such as cognitive function, weight management, food cravings, mood and glucose metabolism.

Other Nutrition 21 Ingredients

Selenomax is a high selenium yeast that has clinically substantiated benefits in promoting immune function. Selenium is an essential trace mineral antioxidant necessary for a healthy immune system.

SelenoPure is a yeast-free, highly bioavailable source of selenium that has clinically substantiated benefits in supporting a healthy immune system.

Zinmax zinc picolinate, made in the U.S., is a source of the essential trace mineral zinc that has clinically substantiated benefits. Zinmax zinc picolinate is often included in formulas for immune support, vision health, pregnancy (when doctor-approved), sexual health, fertility, bone and joint support and children’s health.

New sports nutrition focused products are in development and anticipated for launch in 2016.