Japan Bio Science Laboratory is manufacturer of high quality functional ingredients. JBSL is the pioneer in the research of nattokinase, and in 1998 was the first company in the world to isolate and market this unique enzyme. NSK-SD® is fermented using JBSL’s patented strain of Bacillus subtilis natto. JBSL also has patented the removal of Vitamin K2 from nattokinase. JBSL values continuing research and generates two new clinical studies per year on NSK-SD®.