self-GRAS conclusions

Associations Respond to Mandatory GRAS Notification Proposal

by Shari Barbanel | August 19, 2026

The U.S. Department of Health and Human Services (HHS) and U.S. Food and Drug Administration (FDA) proposed a rule requiring manufacturers to notify FDA whenever they conclude the use of a substance added to human or animal food is generally recognized as safe (GRAS). Since Congress established the GRAS exemption in 1958, manufacturers have been ...

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