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Herbalife’s Aloin Identification Method for Aloe Vera Officially Recognized by AOAC INTERNATIONAL

by Shari Barbanel | July 9, 2025

Herbalife_Brandmark_Primary_Garden_Green_CMYKHerbalife Ltd. (Los Angeles, CA) has announced the Association of Official Analytical Collaboration (AOAC INTERNATIONAL)—a global authority in analytical science—has formally certified its proprietary method for identifying and measuring anthraquinones, also known as aloins, in aloe vera. Aloe regulatory groups require producers of ingestible aloe vera products to monitor naturally occurring compounds such as aloin A, aloin B and aloe-emodin to meet safety guidelines. This certification officially recognizes Herbalife’s longstanding method as the world’s first AOAC-approved approach for detecting aloins—reinforcing safety and quality benchmarks across botanical and dietary supplement industries.

Developed by Herbalife scientists and validated by independent laboratories worldwide, this AOAC-certified method is used to test every batch of Herbalife’s aloe-based products, ensuring safety, while preserving aloe vera’s natural benefits. Aloe vera is a key ingredient in many of Herbalife’s top products, which are sold in more than 90 markets.

Hand pouring Herbal Aloe Concentrate original flavor into glass“This AOAC validation is an important milestone for Herbalife and the industry as a whole,” said Gary Swanson, senior vice president of global quality at Herbalife and lead author of the study. “We are proud to lead scientific innovation that enhances botanical ingredient safety, benefitting not only Herbalife products and our customers, but also advancing standards across the industry.”

Herbalife’s method was validated through a global multi-laboratory study involving eight independent laboratories, according to the company. Each lab tested the same set of six aloe vera samples, including both raw materials and finished products, using HPLC (high-performance liquid chromatography) to measure aloin A, aloin B, and aloe-emodin. The study ensured the method’s accuracy and reliability across various labs and product types, with results confirming that it met all performance criteria, including precision and system suitability.

“This multi-laboratory validation study supported approval of an analytical method developed by Herbalife scientists as the AOAC 2016.09 Official Final Action Method,” said Dr. Katerina Mastovska, deputy executive director and chief science officer, AOAC INTERNATIONAL. “AOAC official methods undergo rigorous scientific evaluation and are highly credible and globally accepted. As such, this method will help strengthen botanical quality and safety standards worldwide.”

Herbalife’s aloe vera testing method has been published in Journal of AOAC INTERNATIONAL (Volume 108, Issue 3, Pages 449-471).

For more information, visit https://ir.herbalife.com/.

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